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Article

Cross-species hybridization of microarrays for studying tumor transcriptome of brain metastasis

10 Oct 2011

Abstract excerpt

Although the importance of the cellular microenvironment (soil) during invasion and metastasis of cancer cells (seed) has been well-recognized, technical challenges have limited the ability to assess the influence of the microenvironment on cancer cells at the molecular level. Here, we show that an experimental strategy, competitive cross-species hybridization of microarray experiments, can characterize the...

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PMID: 21987811
DOI: 10.1073/pnas.1114210108

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