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Article

Tumor–stromal interactions reciprocally modulate gene expression patterns during carcinogenesis and metastasis

15 Feb 2006

Abstract excerpt

This study used a unique xenogeneic breast cancer model to study the effects of tumor cells and neighboring host cells upon each other in tumor growth and metastasis. It exploited species differences between the interacting components to determine how the host influenced the tumor and vice versa. It was found that the gene expression profiles of highly and poorly metastatic clones from the same human breast...

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Identifiers

PMID: 16482564
DOI: 10.1002/ijc.21757

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Source receipt: pubmed, retrieved 7 Sept 2026.

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