Article
Immunogenic and tolerogenic signatures in human immunodeficiency virus (HIV)-infected controllers compared with progressors and a conversion strategy of virus control.
Clinical and experimental immunology - 1 Nov 2011
Whittall T, Peters B, Rahman D, Kingsley C I, Vaughan R, Lehner T
Abstract excerpt
Epidemiological studies have identified a small cohort of controllers of human immunodeficiency virus (HIV)-1 infection, who without treatment have no detectable virus, and others who progress at a variable rate. The objective of this study was to distinguish immune signatures in HIV controllers and progressors, by evaluating tolerogenic and immunogenic factors in untreated HIV-1 infected individuals. The...
Topics
- Antibodies, Monoclonal
- Antigens, CD
- Antigens, Differentiation, T-Lymphocyte
- B7-H1 Antigen
- CD40 Ligand
- CTLA-4 Antigen
- Chemokine CCL3
- Chemokine CCL4
- Disease Progression
- Flow Cytometry
- HIV Infections
- HIV Long-Term Survivors
- HIV-1