Article
Elevated c-myc expression in childhood medulloblastomas.
Pediatric research - 1 Jul 1990
MacGregor D N, Ziff E B
Abstract excerpt
Medulloblastoma is a rare brain tumor usually occurring in late childhood or early adolescence. Little is known regarding the cell of origin or cellular events leading to its malignant transformation. We have studied the expression of developmentally regulated mRNA in tumor samples by the Northern hybridization assay to determine a relative stage at which a block to further differentiation occurs. In a series of...
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