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Article

Regulation of septin dynamics by the Saccharomyces cerevisiae lysine acetyltransferase NuA4.

PloS one - 1 Jan 2011

Mitchell Leslie, Lau Andrea, Lambert Jean-Philippe, Zhou Hu, Fong Ying, Couture Jean-François, Figeys Daniel, Baetz Kristin

Abstract excerpt

In the budding yeast Saccharomyces cerevisiae, the lysine acetyltransferase NuA4 has been linked to a host of cellular processes through the acetylation of histone and non-histone targets. To discover proteins regulated by NuA4-dependent acetylation, we performed genome-wide synthetic dosage lethal screens to identify genes whose overexpression is toxic to non-essential NuA4 deletion mutants. The resulting...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21984913
DOI: 10.1371/journal.pone.0025336
PMCID: PMC3184947

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Regulation of septin dynamics by the Saccharomyces cerevisiae lysine acetyltransferase NuA4.PMID 21984913Read ↗

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A comprehensive synthetic genetic interaction network governing yeast histone acetylation and deacetylation.Semantic proximity Read ↗

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