Article
The association of ACE I/D gene polymorphism with severe carotid atherosclerosis in patients undergoing carotid endarterectomy.
Journal of the renin-angiotensin-aldosterone system : JRAAS - 1 Mar 2012
Kolaković Ana, Zivković Maja, Radak Djordje, Djurić Tamara, Koncar Igor, Davidović Lazar, Dincić Dragan, Alavantić Dragan, Stanković Aleksandra
Abstract excerpt
INTRODUCTION: The ACE I/D polymorphism was mostly investigated in association with intima-media thickness, rarely with severe atherosclerotic phenotype. MATERIALS AND METHODS: We investigated the association of I/D polymorphism with severe carotid atherosclerosis (CA) (stenosis > 70%) in asymptomatic and symptomatic patients undergoing carotid endarterectomy. The 504 patients subjected to endarterectomy and 492...
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