Article
Association between polymorphisms of the renin angiotensin system and carotid stenosis.
Journal of vascular surgery - 1 Aug 2011
Sticchi Elena, Romagnuolo Ilaria, Sofi Francesco, Pratesi Giovanni, Pulli Raffaele, Pratesi Carlo, Abbate Rosanna, Fatini Cinzia
Abstract excerpt
OBJECTIVE: Carotid stenosis is a common manifestation of systemic atherosclerosis. Apart from traditional risk factors, genetic determinants, such as polymorphisms of the renin angiotensin system (RAS), may be relevant in modulating the atherosclerotic process leading to carotid stenosis. In this study, we investigated the role of angiotensin-converting enzyme (ACE) I/D and -240A>T, angiotensinogen (AGT) M235T,...
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