Article
siRNAs induce efficient RNAi response in Bombyx mori embryos.
PloS one - 1 Jan 2011
Yamaguchi Junichi, Mizoguchi Takayuki, Fujiwara Haruhiko
Abstract excerpt
Short interference RNA (siRNA) is widely used in mammalian cells. In insects, however, reports concerning the suitablility of siRNA in vivo is very limited compared with that of long dsRNA, which is thought to be more effective. There is insufficient information on the essential rules of siRNA design in insects, as very few siRNAs have been tested in this context. To establish an effective method of gene...
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