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Article

PIWI Proteins Play an Antiviral Role in Lepidopteran Cell Lines

30 Jun 2022

Abstract excerpt

Insect antiviral immunity primarily relies on RNAi mechanisms. While a key role of small interfering (si)RNAs and AGO proteins has been well established in this regard, the situation for PIWI proteins and PIWI-interacting (pi)RNAs is not as clear. In the present study, we investigate whether PIWI proteins and viral piRNAs are involved in the immunity against single-stranded RNA viruses in lepidopteran cells,...

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PMID: 35891422
DOI: 10.3390/v14071442

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