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Article

IGF-1 gene polymorphisms in Polish families with high-grade myopia.

Molecular vision - 1 Jan 2011

Rydzanicz Malgorzata, Nowak Dorota M, Karolak Justyna A, Frajdenberg Agata, Podfigurna-Musielak Monika, Mrugacz Malgorzata, Gajecka Marzena

Abstract excerpt

PURPOSE: Recent work has suggested that insulin-like growth factor 1 (IGF-1) gene polymorphisms are genetically linked with high-grade myopia (HM), which is a complex-trait eye disorder in which numerous candidate loci and genes are thought to play a role. We investigated whether the IGF-1 single nucleotide polymorphisms (SNPs) rs6214, rs10860860, and rs2946834 are associated with HM (≤-6.0 diopters [D]) and any...

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PMID: 21976954
PMCID: PMC3185023

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