Article
Cytochrome P450 polymorphism and postoperative cognitive dysfunction.
Minerva anestesiologica - 1 Mar 2012
Steinmetz J, Jespersgaard C, Dalhoff K, Hedley P, Abildstrøm H, Christiansen M, Rasmussen L S
Abstract excerpt
BACKGROUND: The etiology of postoperative cognitive dysfunction (POCD) remains unclear but toxicity of anesthetic drugs and their metabolites could be important. We aimed to assess the possible association between POCD after propofol anesthesia and various phenotypes owing to polymorphisms in cytochrome P450 encoding genes. METHODS: We included patients who underwent non-cardiac surgery under total intravenous...
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