Article
Behavioral improvement after chronic administration of coenzyme Q10 in P301S transgenic mice.
Journal of Alzheimer's disease : JAD - 1 Jan 2012
Elipenahli Ceyhan, Stack Cliona, Jainuddin Shari, Gerges Meri, Yang Lichuan, Starkov Anatoly, Beal M Flint, Dumont Magali
Abstract excerpt
Coenzyme Q10 is a key component of the electron transport chain which plays an essential role in ATP production and also has antioxidant effects. Neuroprotective effects of coenzyme Q10 have been reported in both in vitro and in vivo models of neurodegenerative diseases. However, its effects have not been studied in cells or in animals with tau induced pathology. In this report, we administered coenzyme Q10 to...
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