Article
HIV type 1 integrase polymorphisms in treatment-naive and treatment-experienced HIV type 1-infected patients in Thailand where HIV type 1 subtype A/E predominates.
AIDS research and human retroviruses - 1 Aug 2012
Phuphuakrat Angsana, Pasomsub Ekawat, Kiertiburanakul Sasisopin, Chantratita Wasun, Sungkanuparph Somnuek
Abstract excerpt
Integrase inhibitor (INI) is a novel antiretroviral drug recommended for both treatment-naive and treatment-experienced HIV-1-infected patients. Limited data are available on INI resistance in Thailand, where HIV-1 subtype A/E predominates. We aimed to investigate INI resistance-associated mutations (RAMs) among treatment-naive patients and patients who experienced treatment failure with NNRTI-based or PI-based...
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