Article
Comparison of protease inhibitor (PI) resistance-associated mutations between PI-naïve and PI-experienced HIV-1 infected patients in Thailand where subtype A/E is predominant.
Current HIV research - 1 Sept 2010
Wiboonchutikul Surasak, Sungkanuparph Somnuek, Sukasem Chonlaphat, Wathipthun Chorthip, Chantratita Wasun
Abstract excerpt
Protease inhibitor (PI) resistance-associated mutations (RAMs) are commonly observed in PI-naïve patients who infected with HIV-1 subtype A/E. Few data are available on the genetic mechanisms of PI resistance in non-B HIV-1. This study was aimed to compare PI-RAMs between PI-naïve and -experienced patients and determine PI resistance in each group. Genotypic resistance testing was conducted among a cohort of...
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