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Targeting survivin and p53 in pediatric acute lymphoblastic leukemia

30 Sept 2011

Abstract excerpt

Despite advances in treatment and outcomes for patients with pediatric acute lymphoblastic leukemia (ALL), there continue to be subsets of patients who are refractory to standard chemotherapy and hematopoietic stem cell transplant. Therefore, novel gene targets for therapy are needed to further advance treatment for this disease. RNA interference technology has identified survivin as a potential therapeutic...

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Share to Acute Lymphoblastic Leukemia research
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Identifiers

PMID: 21960246
DOI: 10.1038/leu.2011.249

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