Article
WT1 in disease: shifting the epithelial-mesenchymal balance.
The Journal of pathology - 1 Jan 2012
Miller-Hodges Eve, Hohenstein Peter
Abstract excerpt
WT1 is a versatile gene that controls transitions between the mesenchymal and epithelial state of cells in a tissue-context dependent manner. As such, WT1 is indispensable for normal development of many organs and tissues. Uncontrolled epithelial to mesenchymal transition (EMT) is a hallmark of a...
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