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Article

A conserved region in the prM protein is a critical determinant in the assembly of flavivirus particles

29 Sept 2011

Abstract excerpt

Flaviviruses are assembled to bud into the lumen of the endoplasmic reticulum (ER) and are secreted through the vesicle transport pathway, but the details of the molecular mechanism of virion assembly remain largely unknown. In this study, a highly conserved region in the prM protein was identified among flaviviruses. In the subviral particle (SP) system of tick-borne encephalitis virus (TBEV) and Japanese...

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PMID: 21957123
DOI: 10.1099/vir.0.035964-0

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