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Article

Acute myeloid leukemia of donor origin after allogeneic stem cell transplantation from a sibling who harbors germline XPD and XRCC3 homozygous polymorphisms.

Journal of hematology & oncology - 27 Sept 2011

Diamond Hilda Rachel, Ornellas Maria Helena, Orfao Alberto, Gomes Bernadete E, Campos Mércia M, Fernandez Teresa S, da Silva Roberto I, Alves Gilda, Lage Claudia, da Silva Dayse A, Moellmann-Coelho Arthur, da Cruz Geydson S, Bouzas Luis Fernando, Abdelhay Eliana

Abstract excerpt

A 54-year-old woman was diagnosed with infiltrative ductal breast carcinoma. Two years after treatment, the patient developed an acute myeloid leukemia (AML) which harbored del(11q23) in 8% of the blast cells. The patient was submitted for allogeneic stem cell transplantation (aSCT) from her HLA-compatible sister. Ten months after transplantation, she relapsed with an AML with basophilic maturation characterized...

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Source

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Identifiers

PMID: 21951951
DOI: 10.1186/1756-8722-4-39
PMCID: PMC3197559

Genes

XRCC3
RAD51
XPA
XRCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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