Coat color dilution in mice because of inactivation of the melanoma antigen MART-1.

doi:10.1111/j.1755-148X.2011.00910.x

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Article

Coat color dilution in mice because of inactivation of the melanoma antigen MART-1.

Pigment cell & melanoma research - 1 Jan 2012

Aydin Iraz T, Hummler Edith, Smit Nico P M, Beermann Friedrich

Abstract excerpt

Melanoma antigen recognized by T cells 1 (MART-1) is a melanoma-specific antigen, which has been thoroughly studied in the context of immunotherapy against malignant melanoma and which is found only in the pigment cell lineage. However, its exact function and involvement in pigmentation is not clearly understood. Melanoma antigen recognized by T cells 1 has been shown to interact with the melanosomal proteins...

Topics

Animals
Cells, Cultured
Genetic Vectors
Hair
Hair Color
MART-1 Antigen
Melanins
Melanocytes
Melanosomes
Mice
Mice, Inbred C57BL
Mice, Knockout
Phenotype
Skin
gp100 Melanoma Antigen

Source

Open in PubMed

Identifiers

PMID: 21943097
DOI: 10.1111/j.1755-148X.2011.00910.x

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