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Article

[Role of fibrinogen Bbeta-chain D-region 454-458 residues for assembly and secretion of intact fibrinogen].

Rinsho byori. The Japanese journal of clinical pathology - 1 Aug 2011

Terasawa Fumiko, Takezawa Yuka, Hirota-Kawadobora Masako, Okumura Nobuo

Abstract excerpt

BACKGROUND: To examine the role of fibrinogen Bbeta-chain D region in the assembly and/or secretion of multichain protein, we synthesized eight variant fibrinogens with truncated Bbeta-chains in the C terminal region, terminating with 454, 455, 456 or 458 residues, and with substitution at Bbeta-455Arg by Lys, Ile, Ala or Asp in Chinese hamster ovary (CHO) cells. METHODS: A fibrinogen Bbeta-chain expression...

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PMID: 21942083

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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