Article
[Polymorphism frequency of fibrinogen Bβ-chain 448Arg and Lys, and the differences of plasma fibrinogen level and clotting function with three genotypes in Japanese].
Rinsho byori. The Japanese journal of clinical pathology - 1 Dec 2014
Terasawa Fumiko, Ikeda Minami, Arai Shinpei, Okumura Nobuo
Abstract excerpt
The 448th residue in the fibrinogen Bβ-chain molecule is known to be polymorphic (Arg/Lys, R/K), and its allele frequency was previously estimated to be R: 0.85 and K: 0.15 in the US. In the present study, we collected blood samples from 64 healthy individuals and examined the frequency of the fibrinogen Bβ-chain 448 polymorphism in the Japanese population as well as the relationship between polymorphic types and...
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