Article
[Effect of glycoprotein alpha II bA2334C mutation on the biosynthesis and transportation of alpha II bbeta3 complex].
Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi - 1 Mar 2005
Fu Bin, Chen Fang-ping, Xia Kun, Fu Gan, Liu Wei, Huang Xi-lian, Xiao Guang-fen
Abstract excerpt
OBJECTIVE: To study the effect of glycoprotein (GP) alpha II bA2334C mutation on the biosynthesis and expression of alpha II bbeta3 complex. METHODS: The GP alpha II bA2334C eukaryotic expression plasmid pc3.1-2334M2b was constructed. Chinese hamster ovary (CHO) cells were transfected with the plasmid with or without integrin beta3 expression plasmid pc3.1-3a. The whole expression of alpha II bA2334C was...
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