Article
A genetic association between ß3-aderenoceptor and cholinergic receptor muscarinic 3 polymorphisms in irritable bowel syndrome.
Hepato-gastroenterology - 1 Jan 2000
Onodera Saori, Chiba Toshimi, Sugai Tamotsu, Habano Wataru
Abstract excerpt
BACKGROUND/AIMS: We examined the association of ß3-adrenoceptor (ß3-AR) and cholinergic receptor muscarinic 3 (CHRM3) polymorphisms with irritable bowel syndrome (IBS). METHODOLOGY: DNA was obtained from 81 IBS patients (39 diarrhea type, IBS-D; 25 constipation type, IBS-C, 5 mixed type, IBS-M; and 12 unsubtyped, IBS-U) and 73 controls. For the analyses IBS-(M + U) was combined into one group (NonDNonC). ß3-AR...
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