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HBV GENOTYPIC RESISTANCE TO LAMIVUDINE IN KIDNEY RECIPIENTS AND HEMODIALYZED PATIENTS

1 May 2000

Abstract excerpt

BACKGROUND: Lamivudine is a potent inhibitor of human immunodeficiency virus reverse transcriptase and hepatitis B virus (HBV) DNA polymerase. Its overall efficiency is clearly hampered by relapse at discontinuation and by risk of genotypic resistance. We describe herein the first cases of HBV resistance to lamivudine in kidney recipients and hemodialyzed patients. METHODS: We analyzed 26 HBV-infected kidney...

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PMID: 10852602
DOI: 10.1097/00007890-200005270-00020

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