Article
Genome-wide population-based association study of extremely overweight young adults--the GOYA study.
PloS one - 1 Jan 2011
Paternoster Lavinia, Evans David M, Nohr Ellen Aagaard, Holst Claus, Gaborieau Valerie, Brennan Paul, Gjesing Anette Prior, Grarup Niels, Witte Daniel R, Jørgensen Torben, Linneberg Allan, Lauritzen Torsten, Sandbaek Anelli, Hansen Torben, Pedersen Oluf, Elliott Katherine S, Kemp John P, St Pourcain Beate, McMahon George, Zelenika Diana, Hager Jörg, Lathrop Mark, Timpson Nicholas J, Smith George Davey, Sørensen Thorkild I A
Abstract excerpt
BACKGROUND: Thirty-two common variants associated with body mass index (BMI) have been identified in genome-wide association studies, explaining ∼1.45% of BMI variation in general population cohorts. We performed a genome-wide association study in a sample of young adults enriched for extremely overweight individuals. We aimed to identify new loci associated with BMI and to ascertain whether using an extreme...
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