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Article

Mitochondrial electron transport chain functions in long-lived Ames dwarf mice.

Aging - 1 Aug 2011

Choksi Kashyap B, Nuss Jonathan E, DeFord James H, Papaconstantinou John

Abstract excerpt

The age-associated decline in tissue function has been attributed to ROS-mediated oxidative damage due to mitochondrial dysfunction. The long-lived Ames dwarf mouse exhibits resistance to oxidative stress, a physiological characteristic of longevity. It is not known, however, whether there are differences in the electron transport chain (ETC) functions in Ames tissues that are associated with their longevity. In...

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Identifiers

PMID: 21934186
DOI: 10.18632/aging.100357
PMCID: PMC3184977

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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