Article
Long-lived Ames dwarf mouse exhibits increased antioxidant defense in skeletal muscle.
Mechanisms of ageing and development - 1 Apr 2004
Romanick Mark A, Rakoczy Sharlene G, Brown-Borg Holly M
Abstract excerpt
Resting and exercised (both acute and chronic) hindlimb skeletal muscle from long-lived Ames dwarf and wild type mice at 3, 12, 18, and 24 months of age was tested for antioxidant enzyme activity and protein, non-enzymatic antioxidant ratios, mitochondrial hydrogen peroxide concentration, and plasma lactate levels. Differences were observed in GPX enzyme activity between mouse genotypes at all physical activity...
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