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Article

Myocyte aging and mitochondrial turnover.

Experimental gerontology - 1 May 2004

Terman Alexei, Brunk Ulf T

Abstract excerpt

Cardiac myocytes, skeletal muscle fibers, and other long-lived postmitotic cells show dramatic age-related alterations that mainly affect mitochondria and the lysosomal compartment. Mitochondria are primary sites of reactive oxygen species formation that causes progressive damage to mitochondrial DNA and proteins in parallel to intralysosomal lipofuscin accumulation. There is amassing evidence that several...

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Source

Identifiers

PMID: 15130664
DOI: 10.1016/j.exger.2004.01.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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