Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The daily rhythms of mitochondrial gene expression and oxidative stress regulation are altered by aging in the mouse liver.

Chronobiology international - 1 Jan 2015

Gong Changxia, Li Chengwei, Qi Xiaoqing, Song Zhiyin, Wu Jianguo, Hughes Michael E, Li Xiaodong

Abstract excerpt

The circadian clock regulates many cellular processes, notably including the cell cycle, metabolism and aging. Mitochondria play essential roles in metabolism and are the major sites of reactive oxygen species (ROS) production in the cell. The clock regulates mitochondrial functions by driving daily changes in NAD(+) levels and Sirt3 activity. In addition to this central route, in the present study, we find that...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aging
Share to Circadian Clocks

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Circadian Rhythm

Share to CLOCK Proteins

Share to Mitochondria, Liver

Share to Models, Animal

Share to Oxidative Stress

Share to Reactive Oxygen Species

Source

Identifiers

PMID: 26512910
DOI: 10.3109/07420528.2015.1085388

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The daily rhythms of mitochondrial gene expression and oxidative stress regulation are altered by aging in the mouse liver.PMID 26512910Read ↗

Circadian gene Clock regulates mitochondrial morphology and functions by posttranscriptional waySemantic proximity Read ↗

Circadian Rhythms and Mitochondria: Connecting the DotsSemantic proximity Read ↗

Mouse Models of Oxidative Stress Indicate a Role for Modulating Healthy AgingSemantic proximity Read ↗

Aging triggers mitochondrial, endoplasmic reticulum, and metabolic stress responses in the heartSemantic proximity Read ↗

Circadian Regulation of Gene Expression and Metabolism in the LiverSemantic proximity Read ↗

Respiratory function decline and DNA mutation in mitochondria, oxidative stress and altered gene expression during aging.Semantic proximity Read ↗

Tissue-Specific Profiling of Oxidative Stress-Associated Transcriptome in a Healthy Mouse ModelSemantic proximity Read ↗

NADH dehydrogenase reverses dietary and clock metabolic syndromeSemantic proximity Read ↗

Non-alcoholic steatohepatitis disrupts diurnal liver transcriptome rhythms in miceSemantic proximity Read ↗

Generation and Identification of Mutations Resulting in Chronic and Age-Related Phenotypes in Mice.Semantic proximity Read ↗

An mtDNA mutation accelerates liver aging by interfering with the ROS response and mitochondrial life cycle.Semantic proximity Read ↗

Nonalcoholic Steatohepatitis Disrupts Diurnal Liver Transcriptome Rhythms in MiceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.