Article
Contribution of resistance-nodulation-division efflux pump operon smeU1-V-W-U2-X to multidrug resistance of Stenotrophomonas maltophilia.
Antimicrobial agents and chemotherapy - 1 Dec 2011
Chen Chao-Hsien, Huang Chiang-Ching, Chung Tsao-Chuen, Hu Rouh-Mei, Huang Yi-Wei, Yang Tsuey-Ching
Abstract excerpt
KJ09C, a multidrug-resistant mutant of Stenotrophomonas maltophilia KJ, was generated by in vitro selection with chloramphenicol. The multidrug-resistant phenotype of KJ09C was attributed to overexpression of a resistance nodulation division (RND)-type efflux system encoded by an operon consisting of five genes: smeU1, smeV, smeW, smeU2, and smeX. Proteins encoded by smeV, smeW, and smeX were similar to the...
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