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Article

The SmeYZ efflux pump of Stenotrophomonas maltophilia contributes to drug resistance, virulence-related characteristics, and virulence in mice.

Antimicrobial agents and chemotherapy - 1 Jul 2015

Lin Yi-Tsung, Huang Yi-Wei, Chen Shiang-Jiuun, Chang Chia-Wei, Yang Tsuey-Ching

Abstract excerpt

The resistance-nodulation-division (RND)-type efflux pump is one of the causes of the multidrug resistance of Stenotrophomonas maltophilia. The roles of the RND-type efflux pump in physiological functions and virulence, in addition to antibiotic extrusion, have attracted much attention. In this study, the contributions of the constitutively expressed SmeYZ efflux pump to drug resistance, virulence-related...

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PMID: 25918140
DOI: 10.1128/AAC.00372-15
PMCID: PMC4468721

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