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Article

Interplay between intrinsic and acquired resistance to quinolones in Stenotrophomonas maltophilia.

Environmental microbiology - 1 May 2014

García-León Guillermo, Salgado Fabiola, Oliveros Juan Carlos, Sánchez María Blanca, Martínez José Luis

Abstract excerpt

To analyse whether the mutation-driven resistance-acquisition potential of a given bacterium might be a function of its intrinsic resistome, quinolones were used as selective agents and Stenotrophomonas maltophilia was chosen as a bacterial model. S. maltophilia has two elements - SmQnr and SmeDEF - that are important in intrinsic resistance to quinolones. Using a battery of mutants in which either or both of...

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PMID: 24447641
DOI: 10.1111/1462-2920.12408

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