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Article

Overexpression of the multidrug efflux pump SmeDEF impairs Stenotrophomonas maltophilia physiology.

The Journal of antimicrobial chemotherapy - 1 Mar 2004

Alonso Ana, Morales Gracia, Escalante Ricardo, Campanario Ester, Sastre Leandro, Martinez Jose L

Abstract excerpt

OBJECTIVES: The use of antibiotics for the treatment of infectious diseases has led to important changes in the structure of pathogenic bacterial populations. However, these changes could be buffered if the expression of antibiotic resistance genes were to lead to the counter-selection of antibio...

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Identifiers

PMID: 14739147
DOI: 10.1093/jac/dkh074

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14739147-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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Overexpression of the multidrug efflux pump SmeDEF impairs Stenotrophomonas maltophilia physiology.PMID 14739147Read ↗

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The SmeYZ efflux pump of Stenotrophomonas maltophilia contributes to drug resistance, virulence-related characteristics, and virulence in mice.Semantic proximity Read ↗

Efflux pump systems as key contributors to multidrug resistance in Stenotrophomonas maltophilia: Physiological roles and gene regulationSemantic proximity Read ↗

Mechanisms of antimicrobial resistance in Stenotrophomonas maltophilia: a review of current knowledge.Semantic proximity Read ↗

Expression of Sme efflux pumps and multilocus sequence typing in clinical isolates of Stenotrophomonas maltophilia.Semantic proximity Read ↗

Overexpression of the Efflux Pumps SmeVWX and SmeDEF Is a Major Cause of Resistance to Co-trimoxazole in Stenotrophomonas maltophilia.Semantic proximity Read ↗

Antimicrobial Peptide Exposure Selects for Resistant and Fit Stenotrophomonas maltophilia Mutants That Show Cross-Resistance to Antibiotics.Semantic proximity Read ↗

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