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Article

Significance testing in ridge regression for genetic data.

BMC bioinformatics - 19 Sept 2011

Cule Erika, Vineis Paolo, De Iorio Maria

Abstract excerpt

BACKGROUND: Technological developments have increased the feasibility of large scale genetic association studies. Densely typed genetic markers are obtained using SNP arrays, next-generation sequencing technologies and imputation. However, SNPs typed using these methods can be highly correlated due to linkage disequilibrium among them, and standard multiple regression techniques fail with these data sets due to...

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Identifiers

PMID: 21929786
DOI: 10.1186/1471-2105-12-372
PMCID: PMC3228544

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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