Wiring the oncogenic circuitry: Pin1 unleashes mutant p53

Abstract excerpt

Unlike several tumor suppressor genes, whose inactivation is due to deletions or truncating mutations, TP53 is most frequently hit by missense mutations in its DNA binding domain.

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cell death mechanisms and regulation
• Share to Neuroblastoma Research and Treatments
• Share to Signaling Pathways in Disease