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Article

Influence of renal dysfunction phenotype on mortality in the setting of cardiac dysfunction: analysis of three randomized controlled trials.

European journal of heart failure - 1 Nov 2011

Testani Jeffrey M, Coca Steven G, Shannon Richard P, Kimmel Stephen E, Cappola Thomas P

Abstract excerpt

AIMS: Renal neurohormonal activation leading to a reduction in glomerular filtration rate (GFR) has been suggested as a mechanism for renal insufficiency (RI) in the setting of heart failure. We hypothesized that RI occurring in the presence of renal neurohormonal activation may be prognostically more important than RI in the absence of renal neurohormonal activation. METHODS AND RESULTS: Subjects in the...

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Identifiers

PMID: 21926073
DOI: 10.1093/eurjhf/hfr123
PMCID: PMC3200208

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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