Article
Phenotyping of Fontan-Associated Renal Physiology and Disease.
Comprehensive Physiology - 1 Apr 2026
van Hassel Gaston, Ter Maaten Jozine M, Beldhuis Iris E, Liem Eryn T, Zwart Bastiaan, Bakker Stephan J L, Berger Rolf M F, van Melle Joost P
Abstract excerpt
BACKGROUND: Kidney dysfunction is prevalent but insufficiently understood in Fontan patients. We aimed to investigate Fontan-Associated Renal Disease (FARD) through comprehensive phenotyping using biomarkers of renal function and injury, as well as ultrasound assessment of intrarenal hemodynamics. METHODS: We prospectively collected data on serum creatinine and cystatin C levels, and 24-h urine creatinine...
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