Article
A combined-biomarker approach to clinical phenotyping renal dysfunction in heart failure.
Journal of cardiac failure - 1 Dec 2014
Testani Jeffrey M, Damman Kevin, Brisco Meredith A, Chen Susan, Laur Olga, Kula Alexander J, Tang W H Wilson, Parikh Chirag
Abstract excerpt
BACKGROUND: Differentiating heart failure (HF) induced renal dysfunction (RD) from intrinsic kidney disease is challenging. It has been demonstrated that biomarkers such as B-type natriuretic peptide (BNP) or the blood urea nitrogen to creatinine ratio (BUN/creat) can identify high- vs low-risk RD. Our objective was to determine if combining these biomarkers could further improve risk stratification and clinical...
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