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Article

Low- and High-renin Heart Failure Phenotypes with Clinical Implications.

Clinical chemistry - 1 Mar 2018

Pavo Noemi, Goliasch Georg, Wurm Raphael, Novak Johannes, Strunk Guido, Gyöngyösi Mariann, Poglitsch Marko, Säemann Marcus D, Hülsmann Martin

Abstract excerpt

BACKGROUND: Blockade of the renin-angiotensin system (RAS) represents a main strategy in the therapy of heart failure with reduced ejection fraction (HFrEF), but the role of active renin concentration (ARC) for guiding therapy in the presence of an RAS blockade remains to be established. This study assessed angiotensin profiles of HFrEF patients with distinct RAS activations as reflected by ARC. METHODS: Two...

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Source

Identifiers

PMID: 29138270
DOI: 10.1373/clinchem.2017.278705

Genes

ARC
ACE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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