Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clinical significance of UNC5B expression in colorectal cancer

15 Sept 2011

Abstract excerpt

The purpose of this study was to find a methylation-related gene that could become a biomarker or therapeutic target in colorectal carcinoma (CRC). We screened candidate genes suspected to be silenced by DNA methylation using cDNA microarray analysis. To investigate the clinical significance of one candidate gene (UNC5B), we analyzed the correlation between mRNA expression and clinicopathological features using...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related molecular mechanisms research
Share to Epigenetics and DNA Methylation
Share to Ferroptosis and cancer prognosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 21922135
DOI: 10.3892/ijo.2011.1201

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 9 closest

Clinical significance of UNC5B expression in colorectal cancerPMID 21922135Read ↗

Methylation of the UNC5C gene is frequently detected in hepatocellular carcinoma.Semantic proximity Read ↗

Epigenetic and genetic alterations in Netrin-1 receptors UNC5C and DCC in human colon cancer.Semantic proximity Read ↗

Variants in the netrin-1 receptor UNC5C prevent apoptosis and increase risk of familial colorectal cancer.Semantic proximity Read ↗

Gene Expression Signature and the Prediction of Ulcerative Colitis–Associated Colorectal Cancer by DNA MicroarraySemantic proximity Read ↗

A microRNA-7 binding site polymorphism in HOXB5 leads to differential gene expression in bladder cancer.Semantic proximity Read ↗

Inactivation of MYO5B promotes invasion and motility in gastric cancer cells.Semantic proximity Read ↗

<i>MUC12</i> mRNA expression is an independent marker of prognosis in stage II and stage III colorectal cancerSemantic proximity Read ↗

Functional elucidation and methylation-mediated downregulation of ITGA5 gene in breast cancer cell line MDA-MB-468.Semantic proximity Read ↗

Serum Level and Tumor Tissue Expression of Ribonucleotide-Diphosphate Reductase Subunit M2 B: A Potential Biomarker for Colorectal CancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.