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Article

The awakening of an advanced malignant cancer: an insult to the mitochondrial genome.

Biochimica et biophysica acta - 1 May 2012

Cook Cody C, Higuchi Masahiro

Abstract excerpt

BACKGROUND: In only months-to-years a primary cancer can progress to an advanced phenotype that is metastatic and resistant to clinical treatments. As early as the 1900s, it was discovered that the progression of a cancer to the advanced phenotype is often associated with a shift in the metabolic...

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Identifiers

PMID: 21920409
DOI: 10.1016/j.bbagen.2011.08.017
PMCID: PMC3269539

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21920409-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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