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Article

Relevance of mitochondrial genetics and metabolism in cancer development.

Cold Spring Harbor perspectives in biology - 1 Feb 2013

Gasparre Giuseppe, Porcelli Anna Maria, Lenaz Giorgio, Romeo Giovanni

Abstract excerpt

Cancer cells are characterized in general by a decrease of mitochondrial respiration and oxidative phosphorylation, together with a strong enhancement of glycolysis, the so-called Warburg effect. The decrease of mitochondrial activity in cancer cells may have multiple reasons, related either to t...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23378588
DOI: 10.1101/cshperspect.a011411
PMCID: PMC3552507

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23378588-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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