Article
Structure of the Lassa virus nucleoprotein revealed by X-ray crystallography, small-angle X-ray scattering, and electron microscopy.
The Journal of biological chemistry - 4 Nov 2011
Brunotte Linda, Kerber Romy, Shang Weifeng, Hauer Florian, Hass Meike, Gabriel Martin, Lelke Michaela, Busch Carola, Stark Holger, Svergun Dmitri I, Betzel Christian, Perbandt Markus, Günther Stephan
Abstract excerpt
The nucleoprotein (NP) of Lassa virus (LASV) strain AV was expressed in a recombinant baculovirus system. The crystal structure of full-length NP was solved at a resolution of 2.45 Å. The overall fold corresponds to that of NP of LASV strain Josiah (Qi, X., Lan, S., Wang, W., Schelde, L. M., Dong, H., Wallat, G. D., Ly, H., Liang, Y., and Dong, C. (2010) Nature 468, 779-783) with a root mean square deviation of...
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