Article
Housekeeping gene variability in the liver of alcoholic patients.
Alcoholism, clinical and experimental research - 1 Feb 2012
Boujedidi Hédia, Bouchet-Delbos Laurence, Cassard-Doulcier Anne-Marie, Njiké-Nakseu Micheline, Maitre Sophie, Prévot Sophie, Dagher Ibrahim, Agostini Hélène, Voican Cosmin S, Emilie Dominique, Perlemuter Gabriel, Naveau Sylvie
Abstract excerpt
BACKGROUND: Quantification of gene expression using reverse transcription-quantitative polymerase chain reaction (RT-qPCR) requires normalization to an endogenous reference gene termed housekeeping gene (HKG). Many of the commonly used HKGs are regulated and vary under experimental conditions and disease stages. Alcoholic liver disease (ALD) is associated with several different liver histological lesions that may...
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