Article
Development and initial characterization of a HAPPY panel for mapping the X. tropicalis genome.
International journal of biological sciences - 1 Jan 2011
Jiang Zhihua, Michal Jennifer J, Beckman Kenneth B, Lyons Jessica B, Zhang Ming, Pan Zengxiang, Rokhsar Daniel S, Harland Richard M
Abstract excerpt
HAPPY mapping was designed to pursue the analysis of approximately random HAPloid DNA breakage samples using the PolYmerase chain reaction for mapping genomes. In the present study, we improved the method and integrated two other molecular techniques into the process: whole genome amplification and the Sequenom SNP (single nucleotide polymorphism) genotyping assay in order to facilitate whole genome mapping of X....
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