Article
A truncation mutant of Csf3r cooperates with PML-RARα to induce acute myeloid leukemia in mice.
Experimental hematology - 1 Dec 2011
Kunter Ghada, Woloszynek Jill R, Link Daniel C
Abstract excerpt
Severe congenital neutropenia is associated with a marked propensity to develop myelodysplasia or acute myeloid leukemia (AML). Truncation mutations of CSF3R, encoding the granulocyte colony-stimulating factor receptor (G-CSFR), are associated with development of myelodysplasia/AML in severe cong...
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