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Article

No evidence for strong recent positive selection favoring the 7 repeat allele of VNTR in the DRD4 gene.

PloS one - 1 Jan 2011

Naka Izumi, Nishida Nao, Ohashi Jun

Abstract excerpt

The human dopamine receptor D4 (DRD4) gene contains a 48-bp variable number of tandem repeat (VNTR) in exon 3, encoding the third intracellular loop of this dopamine receptor. The DRD4 7R allele, which seems to have a single origin, is commonly observed in various human populations and the nucleotide diversity of the DRD4 7R haplotype at the DRD4 locus is reduced compared to the most common DRD4 4R haplotype....

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Source

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Identifiers

PMID: 21909391
DOI: 10.1371/journal.pone.0024410
PMCID: PMC3164202

Genes

DRD4

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Source receipt: pubmed, retrieved 7 Sept 2026.

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