Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Failure to replicate an excess of the long dopamine D4 exon III repeat polymorphism in ADHD in a family-based study.

American journal of medical genetics - 12 Jun 2000

Kotler M, Manor I, Sever Y, Eisenberg J, Cohen H, Ebstein R P, Tyano S

Abstract excerpt

The DRD4 exon III repeat polymorphism has been associated in adults with Novelty Seeking personality traits and in children with attention deficit hyperactivity disorder (ADHD) in some but not all studies. In a previous report we failed to observe preferential transmission of the long DRD4 repeat in ADHD compared to the haplotype relative risk (HRR) derived control group in a group of 49 triads (both parents and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Attention Deficit Disorder with Hyperactivity
Share to Exons

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Haplotypes

Share to Likelihood Functions

Share to Receptors, Dopamine D2

Share to Receptors, Dopamine D4

Share to Reproducibility of Results

Share to Tandem Repeat Sequences

Source

Identifiers

PMID: 10898899
DOI: 10.1002/1096-8628(20000612)96:3<278::aid-ajmg8>3.0.co;2-r

Genes

DRD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Failure to replicate an excess of the long dopamine D4 exon III repeat polymorphism in ADHD in a family-based study.PMID 10898899Read ↗

A haplotype relative risk study of the dopamine D4 receptor (DRD4) exon III repeat polymorphism and attention deficit hyperactivity disorder (ADHD).Semantic proximity Read ↗

High prevalence of rare dopamine receptor D4 alleles in children diagnosed with attention-deficit hyperactivity disorder.Semantic proximity Read ↗

No evidence for the association of DRD4 with ADHD in a Taiwanese population within-family study.Semantic proximity Read ↗

Is there a role for rare variants in DRD4 gene in the susceptibility for ADHD? Searching for an effect of allelic heterogeneity.Semantic proximity Read ↗

Failure to replicate an association between the catechol-O-methyltransferase polymorphism and attention deficit hyperactivity disorder in a second, independently recruited Israeli cohort.Semantic proximity Read ↗

No association of the dopamine DRD4 receptor (DRD4) gene polymorphism with attention deficit hyperactivity disorder (ADHD) in the Irish populationSemantic proximity Read ↗

A family-based and case-control association study of the dopamine D4 receptor gene and dopamine transporter gene in attention deficit hyperactivity disorder.Semantic proximity Read ↗

DRD4 rare variants in Attention-Deficit/Hyperactivity Disorder (ADHD): further evidence from a birth cohort study.Semantic proximity Read ↗

The short DRD4 repeats confer risk to attention deficit hyperactivity disorder in a family-based design and impair performance on a continuous performance test (TOVA).Semantic proximity Read ↗

Association of the dopamine receptor D4 (DRD4) gene 7-repeat allele with children with attention-deficit/hyperactivity disorder (ADHD): an update.Semantic proximity Read ↗

Dopamine DRD4 receptor polymorphism and attention deficit hyperactivity disorder.Semantic proximity Read ↗

The dopamine D4 receptor and the hyperactivity phenotype: a developmental-epidemiological study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.