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Article

HLA, PTPN22 and PD-1 associations as markers of autoimmunity in neuromyelitis optica.

Multiple sclerosis (Houndmills, Basingstoke, England) - 1 Jan 2012

Asgari N, Nielsen C, Stenager E, Kyvik K O, Lillevang S T

Abstract excerpt

BACKGROUND: Neuromyelitis optica (NMO) is a disease with autoimmune characteristics. A genetic autoimmune dependency for NMO has not been clarified in detail. OBJECTIVE: To investigate immunogenetic aspects of NMO. METHODS: Forty-one patients with NMO and 42 patients with multiple sclerosis (MS) were diagnosed in a population-based Caucasian cohort. HLA DQA1, DQB1, and DRB1 alleles were determined. Polymorphisms...

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Source

Identifiers

PMID: 21908482
DOI: 10.1177/1352458511417480

Genes

PTPN22

Provenance

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