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Article

Molecular pathophysiology of neurodegenerative disease caused by γPKC mutations.

The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry - 1 Sept 2011

Sakai Norio, Saito Naoaki, Seki Takahiro

Abstract excerpt

OBJECTIVE: Spinocerebellar ataxia type 14 (SCA14) is an autosomal dominant neurodegenerative disorder, which is caused by missense mutations of PRKCG gene encoding γ type protein kinase C (γPKC). To elucidate the pathophysiology of SCA14, we have analyzed the character of mutant γPKC causing SCA1...

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Source

Identifiers

PMID: 21906004
DOI: 10.3109/15622975.2011.598688

Genes

PRKCG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21906004-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Molecular pathophysiology of neurodegenerative disease caused by γPKC mutations.PMID 21906004Read ↗

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